3RB3

Dpo4 extension ternary complex with 3'-terminal primer A base opposite the 1-methylguanine (m1g) lesion

3RB3 の概要

• エントリーDOI: 10.2210/pdb3rb3/pdb
• 関連するPDBエントリー: 3RAQ 3RAX 3RB0
• 分子名称: DNA polymerase IV, DNA (5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3'), DNA (5'-D(*C*CP*TP*AP*AP*CP*(MG1)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ... (7 entities in total)
• 機能のキーワード: dna damage, dna repair, dna replication, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, transferase, transferase-dna complex, lesion bypass, dna polymerase, y-family polymerase, dntp-binding, 1-methylguanine, transferase/dna
• 由来する生物種: Sulfolobus solfataricus; 詳細
• 細胞内の位置: Cytoplasm : Q97W02
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 49863.68

構造登録者

Rechkoblit, O.,Patel, D.J. (登録日: 2011-03-28, 公開日: 2011-06-15, 最終更新日: 2023-09-13)

• 主引用文献: Rechkoblit, O.,Delaney, J.C.,Essigmann, J.M.,Patel, D.J.; Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.; Structure, 19:821-832, 2011; PubMed: 21645853; DOI: 10.1016/j.str.2011.03.020

実験手法

X-RAY DIFFRACTION (2.8 Å)