3RAR

X-ray structure of a bound phosphonate transition state analog and enantioselectivity of Candida rugosa lipase toward chiral carboxylic acids

3RAR の概要

• エントリーDOI: 10.2210/pdb3rar/pdb
• 分子名称: Lipase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: alpha/beta hydrolase fold, hydrolase, calcium binding, (rc, rp)-methyl[1-(methoxy)phenylmethyl]phosphonyl adduct at og of serine 209
• 由来する生物種: Candida rugosa (yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 58075.79

構造登録者

Grochulski, P.,Kazlauskas, R. (登録日: 2011-03-28, 公開日: 2011-04-27, 最終更新日: 2023-09-13)

• 主引用文献: Colton, I.J.,Yin, D.T.,Grochulski, P.,Kazlauskas, R.J.; Insights into the molecular basis of chiral acid recognition by Candida rugosa lipase from an X-ray crystal structure of a bound phosphonate transition state analog; Adv.Synth.Catal., 353:2529-2544, 2011; DOI: 10.1002/adsc.201100459

実験手法

X-RAY DIFFRACTION (2.19 Å)