3R8D

Activation of the Human Nuclear Xenobiotic Receptor PXR by the Reverse Transcriptase-Targeted Anti-HIV Drug PNU-142721

3R8D の概要

• エントリーDOI: 10.2210/pdb3r8d/pdb
• 分子名称: Nuclear receptor subfamily 1 group I member 2, 6-CHLORO-2-(1-FURO[2,3-C]PYRIDIN-5-YL-ETHYLSULFANYL)-PYRIMIDIN-4-YLAMINE (3 entities in total)
• 機能のキーワード: nuclear receptor, pxr, xenobiotic, ligand binding domain, transcription regulation, xenobiotics, endobiotics, transcription
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: O75469
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36587.64

構造登録者

Cheng, Y.,Redinbo, M.R. (登録日: 2011-03-23, 公開日: 2011-08-17, 最終更新日: 2024-02-21)

• 主引用文献: Cheng, Y.,Redinbo, M.R.; Activation of the human nuclear xenobiotic receptor PXR by the reverse transcriptase-targeted anti-HIV drug PNU-142721.; Protein Sci., 20:1713-1719, 2011; PubMed: 21805522; DOI: 10.1002/pro.706

実験手法

X-RAY DIFFRACTION (2.8 Å)