3R88
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS145)
Summary for 3R88
Entry DOI | 10.2210/pdb3r88/pdb |
Related | 2bpq 3QQS 3QR9 3QS8 3QSA 3R6C |
Descriptor | Anthranilate phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | anthranilate phosphoribosyltransferase, anthranilic acids, magnesium, tryptophan, inhibitor, transferase, magnesium binding phosphoribosyl pyrophosphate, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 78602.02 |
Authors | Castell, A.,Short, F.L.,Lott, J.S. (deposition date: 2011-03-23, release date: 2012-09-26, Last modification date: 2024-02-21) |
Primary citation | Castell, A.,Short, F.L.,Evans, G.L.,Cookson, T.V.,Bulloch, E.M.,Joseph, D.D.,Lee, C.E.,Parker, E.J.,Baker, E.N.,Lott, J.S. The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52:1776-1787, 2013 Cited by PubMed: 23363292DOI: 10.1021/bi301387m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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