3R6R

Structure of the complex of an intramolecular human telomeric DNA with Berberine formed in K+ solution

3R6R の概要

• エントリーDOI: 10.2210/pdb3r6r/pdb
• 分子名称: DNA (22-mer), POTASSIUM ION, BERBERINE, ... (4 entities in total)
• 機能のキーワード: dna-drug complex, g-quadruplex, human telomeric dna, dna, dna-antibiotic complex, dna/antibiotic
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 8407.14

構造登録者

Ferraroni, M.,Bazzicalupi, C.,Gratteri, P.,Bilia, A.R. (登録日: 2011-03-22, 公開日: 2012-02-29, 最終更新日: 2023-09-13)

• 主引用文献: Bazzicalupi, C.,Ferraroni, M.,Bilia, A.R.,Scheggi, F.,Gratteri, P.; The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1.; Nucleic Acids Res., 41:632-638, 2013; PubMed: 23104378; DOI: 10.1093/nar/gks1001

実験手法

X-RAY DIFFRACTION (2.4 Å)