3R66

Crystal structure of human ISG15 in complex with NS1 N-terminal region from influenza virus B, Northeast Structural Genomics Consortium Target IDs HX6481, HR2873, and OR2

3R66 の概要

• エントリーDOI: 10.2210/pdb3r66/pdb
• 関連するPDBエントリー: 1XEQ 1Z2M
• 分子名称: Non-structural protein 1, Ubiquitin-like protein ISG15 (3 entities in total)
• 機能のキーワード: structural genomics, psi-biology, northeast structural genomics consortium, nesg, innate immunity, isg15 conjugation, viral protein-antiviral protein complex, viral protein/antiviral protein
• 由来する生物種: Influenza B virus; 詳細
• 細胞内の位置: Host cytoplasm : P03502; Cytoplasm : P05161
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 62471.30

構造登録者

Guan, R.,Ma, L.C.,Krug, R.M.,Montelione, G.T.,Northeast Structural Genomics Consortium (NESG) (登録日: 2011-03-21, 公開日: 2011-06-08, 最終更新日: 2023-09-13)

• 主引用文献: Guan, R.,Ma, L.C.,Leonard, P.G.,Brendan, A.R.,Sridharan, H.,Zhao, C.,Krug, R.M.,Montelione, G.T.; The Structure of the complex of ISG15 and Influenza B virus NS1 Protein: implications for the mechanism of SN1-mediated inhibition of ISG15 conjugation; To be Published,

実験手法

X-RAY DIFFRACTION (2.3 Å)