3R5I

Crystal structure of liganded Hemoglobin complexed with a potent Antisickling agent, INN-312

Summary for 3R5I

• Entry DOI: 10.2210/pdb3r5i/pdb
• Related: 3IC0 3IC2
• Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... (7 entities in total)
• Functional Keywords: heme protein, antisickling, globin fold, oxygen transport, red blood cell, oxygen binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 65693.01

Authors

Safo, M.K.,Musayev, F.N.,Safo, R.P.,Daniels, D.,Eseonu, D.N.,Parra, J. (deposition date: 2011-03-18, release date: 2011-04-06, Last modification date: 2023-09-13)

• Primary citation: Abulmalik, O.,Ghatge, M.S.,Nnamani, I.,Eseonu, D.N.,Musayev, F.N.,Danso-Danquah, R.,Venitz, J.,Asakura, T.,Abraham, D.J.,Safo, M.K.; Structural and in Vitro Chracterization of Pyridyl Derivatives of Benzaldehydes : Highly Potent Antisickling Agents; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)