3R2X

Crystal structure of the de novo designed binding protein HB36.3 in complex the the 1918 influenza virus hemagglutinin

Summary for 3R2X

Entry DOI	10.2210/pdb3r2x/pdb
Descriptor	Hemagglutinin, HB36.3, designed hemagglutinin binding protein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	hemagglutinin, glycoprotein, viral protein-de novo protein complex, viral protein/de novo protein
Biological source	Influenza A virus More
Cellular location	Virion membrane; Single-pass type I membrane protein (Potential): Q9WFX3 Q9WFX3
Total number of polymer chains	3
Total formula weight	68422.32
Authors	Ekiert, D.C.,Wilson, I.A. (deposition date: 2011-03-14, release date: 2011-05-11, Last modification date: 2020-07-29)
Primary citation	Fleishman, S.J.,Whitehead, T.A.,Ekiert, D.C.,Dreyfus, C.,Corn, J.E.,Strauch, E.M.,Wilson, I.A.,Baker, D. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science, 332:816-821, 2011 Cited by PubMed: 21566186 DOI: 10.1126/science.1202617 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation