3R2X

Crystal structure of the de novo designed binding protein HB36.3 in complex the the 1918 influenza virus hemagglutinin

3R2X の概要

• エントリーDOI: 10.2210/pdb3r2x/pdb
• 分子名称: Hemagglutinin, HB36.3, designed hemagglutinin binding protein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: hemagglutinin, glycoprotein, viral protein-de novo protein complex, viral protein/de novo protein
• 由来する生物種: Influenza A virus; 詳細
• 細胞内の位置: Virion membrane; Single-pass type I membrane protein (Potential): Q9WFX3 Q9WFX3
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 68422.32

構造登録者

Ekiert, D.C.,Wilson, I.A. (登録日: 2011-03-14, 公開日: 2011-05-11, 最終更新日: 2020-07-29)

• 主引用文献: Fleishman, S.J.,Whitehead, T.A.,Ekiert, D.C.,Dreyfus, C.,Corn, J.E.,Strauch, E.M.,Wilson, I.A.,Baker, D.; Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.; Science, 332:816-821, 2011; PubMed: 21566186; DOI: 10.1126/science.1202617

実験手法

X-RAY DIFFRACTION (3.1 Å)