3R2A

Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2 and antagonist rhein

Summary for 3R2A

• Entry DOI: 10.2210/pdb3r2a/pdb
• Related: 3R29
• Descriptor: Retinoic acid receptor RXR-alpha, Nuclear receptor corepressor 2, 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, ... (4 entities in total)
• Functional Keywords: nuclear receptor, transcription factor, ligand-binding domain, transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P19793 Q9Y618
• Total number of polymer chains: 6
• Total formula weight: 111490.94

Authors

Zhang, H.,Chen, L.,Chen, J.,Jiang, H.,Shen, X. (deposition date: 2011-03-14, release date: 2011-05-25, Last modification date: 2023-09-13)

• Primary citation: Zhang, H.,Chen, L.,Chen, J.,Jiang, H.,Shen, X.; Structural basis for retinoic x receptor repression on the tetramer.; J.Biol.Chem., 286:24593-24598, 2011; PubMed: 21613212; DOI: 10.1074/jbc.M111.245498

Experimental method

X-RAY DIFFRACTION (3 Å)