3R06

Crystal structure of anti-mouse CD3epsilon antibody 2C11 Fab fragment

Summary for 3R06

• Entry DOI: 10.2210/pdb3r06/pdb
• Related: 3R08
• Descriptor: anti-mouse CD3epsilon antibody 2C11 Fab light chain, anti-mouse CD3epsilon antibody 2C11 Fab heavy chain (3 entities in total)
• Functional Keywords: antibody, anti-cd3epsilon, t-cell receptor, signalling, immune system
• Biological source: Cricetulus migratorius; More
• Total number of polymer chains: 8
• Total formula weight: 187180.87

Authors

Shore, D.A.,Zhu, X.,Wilson, I.A. (deposition date: 2011-03-07, release date: 2012-01-25, Last modification date: 2013-09-11)

• Primary citation: Fernandes, R.A.,Shore, D.A.,Vuong, M.T.,Yu, C.,Zhu, X.,Pereira-Lopes, S.,Brouwer, H.,Fennelly, J.A.,Jessup, C.M.,Evans, E.J.,Wilson, I.A.,Davis, S.J.; T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.; J.Biol.Chem., 287:13324-13335, 2012; PubMed: 22262845; DOI: 10.1074/jbc.M111.332783

Experimental method

X-RAY DIFFRACTION (2.5 Å)