3QWV

Crystal structure of histone lysine methyltransferase SmyD2 in complex with the cofactor product AdoHcy

3QWV の概要

• エントリーDOI: 10.2210/pdb3qwv/pdb
• 分子名称: SET and MYND domain-containing protein 2, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... (4 entities in total)
• 機能のキーワード: methyltransferase, hsp90, transferase
• 由来する生物種: Mus musculus (mouse)
• 細胞内の位置: Cytoplasm, cytosol: Q8R5A0
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 50222.67

構造登録者

Jiang, Y.,Sirinupong, N.,Brunzelle, J.,Yang, Z. (登録日: 2011-02-28, 公開日: 2011-07-06, 最終更新日: 2024-02-21)

• 主引用文献: Jiang, Y.,Sirinupong, N.,Brunzelle, J.,Yang, Z.; Crystal structures of histone and p53 methyltransferase SmyD2 reveal a conformational flexibility of the autoinhibitory C-terminal domain.; Plos One, 6:e21640-e21640, 2011; PubMed: 21738746; DOI: 10.1371/journal.pone.0021640

実験手法

X-RAY DIFFRACTION (2.03 Å)