3QW4

Structure of Leishmania donovani UMP synthase

3QW4 の概要

• エントリーDOI: 10.2210/pdb3qw4/pdb
• 分子名称: UMP synthase, URIDINE-5'-MONOPHOSPHATE, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: n-terminal orotidine monophosphate decarboxylase domain c-terminal orotate phosphoribosyltransferase domain, transferase, lyase
• 由来する生物種: Leishmania donovani
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 99587.25

構造登録者

French, J.B.,Ealick, S.E. (登録日: 2011-02-26, 公開日: 2011-04-20, 最終更新日: 2024-02-21)

• 主引用文献: French, J.B.,Yates, P.A.,Soysa, D.R.,Boitz, J.M.,Carter, N.S.,Chang, B.,Ullman, B.,Ealick, S.E.; The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.; J.Biol.Chem., 286:20930-20941, 2011; PubMed: 21507942; DOI: 10.1074/jbc.M111.228213

実験手法

X-RAY DIFFRACTION (3 Å)