3QUR
Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with MgADP and fosfomycin monophosphate
Summary for 3QUR
Entry DOI | 10.2210/pdb3qur/pdb |
Related | 3D40 3D41 3QUN 3QUO 3QVF 3QVH |
Descriptor | FomA protein, ADENOSINE-5'-DIPHOSPHATE, [(2R,3S)-3-methyloxiran-2-yl]-phosphonooxy-phosphinic acid, ... (5 entities in total) |
Functional Keywords | fosfomycin, antibiotic resistance, phosphoryl transfer, kinase, transferase |
Biological source | Streptomyces wedmorensis |
Total number of polymer chains | 1 |
Total formula weight | 31546.40 |
Authors | Pakhomova, S.,Bartlett, S.G.,Doerner, P.A.,Newcomer, M.E. (deposition date: 2011-02-24, release date: 2011-07-20, Last modification date: 2023-09-13) |
Primary citation | Pakhomova, S.,Bartlett, S.G.,Doerner, P.A.,Newcomer, M.E. Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA. Biochemistry, 50:6909-6919, 2011 Cited by PubMed: 21728358DOI: 10.1021/bi2004334 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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