3QSA
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor TAMU-A7)
3QSA の概要
エントリーDOI | 10.2210/pdb3qsa/pdb |
関連するPDBエントリー | 1ZVW 2BPQ 3QQS 3QR9 3QS8 |
分子名称 | Anthranilate phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, ... (5 entities in total) |
機能のキーワード | anthranilate phosphoribosyltransferase, anthranilic acids, magnesium, tryptophan, magnesium binding phosphoribosyl pyrophosphate, transferase-transferase inhibitor complex, structural genomics, tb structural genomics consortium, tbsgc, transferase/transferase inhibitor |
由来する生物種 | Mycobacterium tuberculosis |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 78805.10 |
構造登録者 | Castell, A.,Short, F.L.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (登録日: 2011-02-20, 公開日: 2012-08-22, 最終更新日: 2024-02-21) |
主引用文献 | Castell, A.,Short, L.F.,Evans, G.,Bulloch, E.M.,Cookson, T.,Parker, E.,Lee, C.,Baker, E.N.,Lott, J.S. Inhibition of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase by blocking of an active site entrance tunnel. To be Published, |
実験手法 | X-RAY DIFFRACTION (2.18 Å) |
構造検証レポート
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