3QO2

Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9

3QO2 の概要

• エントリーDOI: 10.2210/pdb3qo2/pdb
• 分子名称: M-phase phosphoprotein 8, Histone H3 peptide, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: epigenetics, mpp8 phosphorylation, chromodomain, mpp8-h3k9me modulates the expression of e-cadherin, h3k9 methyl-lysine binding, tri-methyl-lysine, dna binding protein-gene regulation complex, histone h3 tail binding protein, dna binding protein/gene regulation
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus : Q99549
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 37072.49

構造登録者

Chang, Y.,Horton, J.R.,Bedford, M.T.,Zhang, X.,Cheng, X. (登録日: 2011-02-09, 公開日: 2011-04-06, 最終更新日: 2023-09-13)

• 主引用文献: Chang, Y.,Horton, J.R.,Bedford, M.T.,Zhang, X.,Cheng, X.; Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9: potential effect of phosphorylation on methyl-lysine binding.; J.Mol.Biol., 408:807-814, 2011; PubMed: 21419134; DOI: 10.1016/j.jmb.2011.03.018

実験手法

X-RAY DIFFRACTION (2.49 Å)