3QJ7

Crystal Structure of the Mycobacterium tuberculosis Thymidylate synthase (ThyA) bound to dUMP

3QJ7 の概要

• エントリーDOI: 10.2210/pdb3qj7/pdb
• 分子名称: Thymidylate synthase, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, SPERMINE, ... (4 entities in total)
• 機能のキーワード: thymidilate synthase, structural genomics, tb structural genomics consortium, tbsgc, transferase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 121322.70

構造登録者

Reddy, M.C.M.,Bruning, J.B.,Harshbarger, W.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 2011-01-28, 公開日: 2011-06-15, 最終更新日: 2023-09-13)

• 主引用文献: Reddy, M.C.M.,Bruning, J.B.,Harshbarger, W.,Sacchettini, J.C.; Crystal structure of binary and ternary complexes of thymidylate synthase (ThyA) from Mycobacterium tuberculosis: insights into the selectivity and mode of inhibition; To be Published,

実験手法

X-RAY DIFFRACTION (2.504 Å)