3QIS

Recognition of the F&H motif by the Lowe Syndrome protein OCRL

3QIS の概要

• エントリーDOI: 10.2210/pdb3qis/pdb
• 分子名称: Inositol polyphosphate 5-phosphatase OCRL-1, Protein FAM109A (3 entities in total)
• 機能のキーワード: dent disease, rac1, rab gtpases, appl1, ses2, endocytic pathway, golgi complex, hydrolase-protein binding complex, hydrolase/protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasmic vesicle, phagosome membrane : Q01968; Early endosome: Q8N4B1
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44243.66

構造登録者

Pirruccello, M.,Swan, L.E.,Folta-Stogniew, E.,De Camilli, P. (登録日: 2011-01-27, 公開日: 2011-06-15, 最終更新日: 2023-09-13)

• 主引用文献: Pirruccello, M.,Swan, L.E.,Folta-Stogniew, E.,De Camilli, P.; Recognition of the F&H motif by the Lowe syndrome protein OCRL.; Nat.Struct.Mol.Biol., 18:789-795, 2011; PubMed: 21666675; DOI: 10.1038/nsmb.2071

実験手法

X-RAY DIFFRACTION (2.3 Å)