3QEL

Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in complex with ifenprodil

Summary for 3QEL

Entry DOI	10.2210/pdb3qel/pdb
Related	3JPW 3QEK 3QEM
Descriptor	NMDA glutamate receptor subunit, Glutamate [NMDA] receptor subunit epsilon-2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	ion channel, nmda receptor, allosteric modulation, phenylethanolamine, n-glycosylation, extracellular, transmembrane, transport protein
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	4
Total formula weight	171681.00
Authors	Karakas, E.,Simorowski, N.,Furukawa, H. (deposition date: 2011-01-20, release date: 2011-06-15, Last modification date: 2023-09-13)
Primary citation	Karakas, E.,Simorowski, N.,Furukawa, H. Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature, 475:249-253, 2011 Cited by PubMed: 21677647 DOI: 10.1038/nature10180 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation