3QCV
Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (18:2)
Summary for 3QCV
Entry DOI | 10.2210/pdb3qcv/pdb |
Descriptor | LT3015 antibody Fab fragment, heavy chain, LT3015 antibody Fab fragment, light chain, (2R)-2-hydroxy-3-(phosphonooxy)propyl (9Z,12Z)-octadeca-9,12-dienoate, ... (4 entities in total) |
Functional Keywords | antibody, lysophosphatidic acid binding, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted : P01834 |
Total number of polymer chains | 4 |
Total formula weight | 96625.94 |
Authors | Fleming, J.K.,Wojciak, J.M.,Campbell, M.-A.,Huxford, T. (deposition date: 2011-01-17, release date: 2011-03-30, Last modification date: 2023-09-13) |
Primary citation | Fleming, J.K.,Wojciak, J.M.,Campbell, M.A.,Huxford, T. Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody. J.Mol.Biol., 408:462-476, 2011 Cited by PubMed: 21392506DOI: 10.1016/j.jmb.2011.02.061 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
Download full validation report