3QBJ

Crystal structure of dipeptidyl peptidase IV in complex with inhibitor

3QBJ の概要

• エントリーDOI: 10.2210/pdb3qbj/pdb
• 関連するPDBエントリー: 3F8S
• 分子名称: Dipeptidyl peptidase 4, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: diabetes mellitus, dipeptidyl-peptidase iv inhibitor, hypoglycemic agent, pyrrolidines, sprague-dawley, structure-activity relationship, hydrolase, glycosylation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 176061.70

構造登録者

Liu, S.P. (登録日: 2011-01-13, 公開日: 2012-01-25, 最終更新日: 2020-07-29)

• 主引用文献: Liu, S.P.; Crystal structure of dipeptidyl peptidase IV in complex with inhibitor; To be Published,

実験手法

X-RAY DIFFRACTION (2.21 Å)