3QAK
Agonist bound structure of the human adenosine A2a receptor
Summary for 3QAK
Entry DOI | 10.2210/pdb3qak/pdb |
Related | 3eml |
Descriptor | Adenosine receptor A2a,lysozyme chimera, 6-(2,2-diphenylethylamino)-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]-N-[2-[(1-pyridin-2-ylpiperidin-4-yl)carbamoylamino]ethyl]purine-2-carboxamide, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (4 entities in total) |
Functional Keywords | structural genomics, protein structure initiative, joint center for innovative membrane protein technologies, jcimpt, membrane protein, receptor, gpcr network, gpcr, signaling protein, hydrolase, psi-biology |
Biological source | Homo Sapien More |
Cellular location | Cell membrane; Multi-pass membrane protein: P29274 |
Total number of polymer chains | 1 |
Total formula weight | 56230.72 |
Authors | Xu, F.,Wu, H.,Katritch, V.,Han, G.W.,Cherezov, V.,Stevens, R.,GPCR Network (GPCR) (deposition date: 2011-01-11, release date: 2011-03-09, Last modification date: 2024-10-09) |
Primary citation | Xu, F.,Wu, H.,Katritch, V.,Han, G.W.,Jacobson, K.A.,Gao, Z.G.,Cherezov, V.,Stevens, R.C. Structure of an agonist-bound human A2A adenosine receptor. Science, 332:322-327, 2011 Cited by PubMed: 21393508DOI: 10.1126/science.1202793 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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