3Q9H
LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold
Summary for 3Q9H
Entry DOI | 10.2210/pdb3q9h/pdb |
Related | 3Q9G 3Q9I 3Q9J |
Descriptor | Cyclic pseudo-peptide LVFFA(ORN)(HAO)LK(ORN), SULFATE ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | beta sheet tetramer, macrocyclic peptide, beta-sheet mimetic, protein fibril |
Total number of polymer chains | 8 |
Total formula weight | 12440.61 |
Authors | Liu, C.,Sawaya, M.R.,Eisenberg, D.,Nowick, J.S.,Cheng, P.,Zheng, J. (deposition date: 2011-01-07, release date: 2011-06-08, Last modification date: 2023-11-15) |
Primary citation | Liu, C.,Sawaya, M.R.,Cheng, P.N.,Zheng, J.,Nowick, J.S.,Eisenberg, D. Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics. J.Am.Chem.Soc., 133:6736-6744, 2011 Cited by PubMed: 21473620DOI: 10.1021/ja200222n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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