3Q65
Human Aldose Reductase in Complex with NADP+ in Space Group P212121
Summary for 3Q65
Entry DOI | 10.2210/pdb3q65/pdb |
Related | 3Q67 |
Descriptor | Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... (5 entities in total) |
Functional Keywords | alpha/beta barrel, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P15121 |
Total number of polymer chains | 2 |
Total formula weight | 74240.15 |
Authors | Sawaya, M.R.,Cascio, D.,Balendiran, G.K. (deposition date: 2010-12-30, release date: 2011-01-19, Last modification date: 2024-02-21) |
Primary citation | Balendiran, G.K.,Sawaya, M.R.,Schwarz, F.P.,Ponniah, G.,Cuckovich, R.,Verma, M.,Cascio, D. The role of Cys-298 in aldose reductase function. J.Biol.Chem., 286:6336-6344, 2011 Cited by PubMed: 21084309DOI: 10.1074/jbc.M110.154195 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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