3Q5L

Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin

3Q5L の概要

• エントリーDOI: 10.2210/pdb3q5l/pdb
• 関連するPDBエントリー: 3H80 3Q5I 3Q5J 3Q5L
• 分子名称: Heat shock protein 83-1, (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-{[2-(pyrrolidin-1-yl)ethyl]amino}-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate (2 entities in total)
• 機能のキーワード: sleeping sickness, leishmania, heat shock protein, structural genomics, structural genomics consortium, sgc, chaperone
• 由来する生物種: Leishmania major
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 107012.99

構造登録者

Wernimont, A.K.,Tempel, W.,Lin, Y.H.,Hutchinson, A.,MacKenzie, F.,Fairlamb, A.,Cossar, D.,Zhao, Y.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Ferguson, M.A.J.,Hui, R.,Pizarro, J.C.,Hills, T.,Structural Genomics Consortium (SGC) (登録日: 2010-12-28, 公開日: 2011-02-23, 最終更新日: 2023-09-13)

• 主引用文献: Wernimont, A.K.,Tempel, W.,Lin, Y.H.,Hutchinson, A.,MacKenzie, F.,Fairlamb, A.,Cossar, D.,Zhao, Y.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Ferguson, M.A.J.,Hui, R.,Pizarro, J.C.,Hills, T.; Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin.; To be Published,

実験手法

X-RAY DIFFRACTION (2.65 Å)