3Q5K

Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor

3Q5K の概要

• エントリーDOI: 10.2210/pdb3q5k/pdb
• 関連するPDBエントリー: 3H80 3Q5I 3Q5J 3Q5L
• 分子名称: Heat shock protein 83-1, 4-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]-2-{[2-(methylsulfanyl)ethyl]amino}benzamide (3 entities in total)
• 機能のキーワード: sleeping sickness, leishmania, heat shock protein, structural genomics, structural genomics consortium, sgc, chaperone
• 由来する生物種: Leishmania major
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26550.95

構造登録者

Wernimont, A.K.,Tempel, W.,Lin, Y.H.,Hutchinson, A.,MacKenzie, F.,Fairlamb, A.,Cossar, D.,Zhao, Y.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Ferguson, M.A.J.,Hui, R.,Pizarro, J.C.,Hills, T.,Structural Genomics Consortium (SGC) (登録日: 2010-12-28, 公開日: 2011-02-23, 最終更新日: 2024-02-21)

• 主引用文献: Wernimont, A.K.,Tempel, W.,Lin, Y.H.,Hutchinson, A.,MacKenzie, F.,Fairlamb, A.,Cossar, D.,Zhao, Y.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Ferguson, M.A.J.,Hui, R.,Pizarro, J.C.,Hills, T.; Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor; To be Published,

実験手法

X-RAY DIFFRACTION (2.35 Å)