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3Q5C

Crystal structure of four-way junction with sticky end

Summary for 3Q5C
Entry DOI10.2210/pdb3q5c/pdb
DescriptorDNA (5'-D(*CP*GP*GP*CP*GP*GP*CP*CP*GP*C)-3') (2 entities in total)
Functional Keywordssticky end, dna
Total number of polymer chains4
Total formula weight12187.92
Authors
Venkadesh, S.,Mandal, P.K.,Gautham, N. (deposition date: 2010-12-28, release date: 2011-05-18, Last modification date: 2023-11-01)
Primary citationVenkadesh, S.,Mandal, P.K.,Gautham, N.
The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice
Biochem.Biophys.Res.Commun., 407:548-551, 2011
Cited by
PubMed Abstract: We report here the crystal structure of the partially self-complementary decameric sequence d(CGGCGGCCGC), which self assembles to form a four-way junction with sticky ends. Each junction binds to four others through Watson-Crick base pairing at the sticky ends to form a rhombic structure. The rhombuses bind to each other and form two dimensional tiles. The tiles stack to form the crystal. The crystal diffracted in the space group P1 to a resolution of 2.5Å. The junction has the anti-parallel stacked-X conformation like other junction structures, though the formation of the rhombic net noticeably alters the details of the junction geometry.
PubMed: 21419105
DOI: 10.1016/j.bbrc.2011.03.056
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.501 Å)
Structure validation

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