3Q5C

Crystal structure of four-way junction with sticky end

3Q5C の概要

• エントリーDOI: 10.2210/pdb3q5c/pdb
• 分子名称: DNA (5'-D(*CP*GP*GP*CP*GP*GP*CP*CP*GP*C)-3') (2 entities in total)
• 機能のキーワード: sticky end, dna
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 12187.92

構造登録者

Venkadesh, S.,Mandal, P.K.,Gautham, N. (登録日: 2010-12-28, 公開日: 2011-05-18, 最終更新日: 2023-11-01)

主引用文献

Venkadesh, S.,Mandal, P.K.,Gautham, N.
The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice
Biochem.Biophys.Res.Commun., 407:548-551, 2011

PubMed Abstract: We report here the crystal structure of the partially self-complementary decameric sequence d(CGGCGGCCGC), which self assembles to form a four-way junction with sticky ends. Each junction binds to four others through Watson-Crick base pairing at the sticky ends to form a rhombic structure. The rhombuses bind to each other and form two dimensional tiles. The tiles stack to form the crystal. The crystal diffracted in the space group P1 to a resolution of 2.5Å. The junction has the anti-parallel stacked-X conformation like other junction structures, though the formation of the rhombic net noticeably alters the details of the junction geometry.

PubMed: 21419105
DOI: 10.1016/j.bbrc.2011.03.056

実験手法

X-RAY DIFFRACTION (2.501 Å)