3Q49

Crystal structure of the TPR domain of CHIP complexed with Hsp70-C peptide

Summary for 3Q49

• Entry DOI: 10.2210/pdb3q49/pdb
• Related: 3Q47 3Q4A
• Descriptor: STIP1 homology and U box-containing protein 1, Hsp70-C peptide (3 entities in total)
• Functional Keywords: e3 ubiquitin ligase, ligase-chaperone complex, ligase/chaperone
• Biological source: Mus musculus (mouse); More
• Cellular location: Cytoplasm: Q9WUD1
• Total number of polymer chains: 2
• Total formula weight: 16592.85

Authors

Wang, L.,Chen, L.,Wu, J.W. (deposition date: 2010-12-23, release date: 2011-03-16, Last modification date: 2023-11-01)

• Primary citation: Wang, L.,Liu, Y.T.,Hao, R.,Chen, L.,Chang, Z.,Wang, H.R.,Wang, Z.X.,Wu, J.W.; Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).; J.Biol.Chem., 286:15883-15894, 2011; PubMed: 21454478; DOI: 10.1074/jbc.M110.201814

Experimental method

X-RAY DIFFRACTION (1.543 Å)