3Q2F

Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand

Summary for 3Q2F

• Entry DOI: 10.2210/pdb3q2f/pdb
• Related: 3G0L
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2B, 4-{4-[3-(1H-imidazol-1-yl)propyl]-5-methyl-4H-1,2,4-triazol-3-yl}-1-methyl-1H-pyrazol-5-amine, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: bazb2, bromodomain adjacent to zinc finger domain, 2b, kiaa1476, walp4, structural genomics consortium, sgc, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (Potential): Q9UIF8
• Total number of polymer chains: 1
• Total formula weight: 14091.19

Authors

Muniz, J.R.C.,Filippakopoulos, P.,Picaud, S.,Felletar, I.,Keates, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-12-20, release date: 2011-01-26, Last modification date: 2023-11-01)

• Primary citation: Muniz, J.R.C.,Filippakopoulos, P.,Picaud, S.,Felletar, I.,Keates, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.; Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (2.06 Å)