3PYX

Crystals Structure of Aspartate beta-Semialdehyde Dehydrogenase complex with NADP and 2-aminoterephthalate

Summary for 3PYX

Entry DOI	10.2210/pdb3pyx/pdb
Related	2GZ2 2GZ3 2PYL 3PWK 3PWS 3PZB 3PZR 3Q0E 3Q11 3Q1L
Descriptor	Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION, ... (6 entities in total)
Functional Keywords	nadp, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological source	Streptococcus pneumoniae
Total number of polymer chains	2
Total formula weight	82202.47
Authors	Pavlovsky, A.G.,Viola, R.E. (deposition date: 2010-12-13, release date: 2012-01-04, Last modification date: 2023-09-13)
Primary citation	Pavlovsky, A.G.,Liu, X.,Faehnle, C.R.,Potente, N.,Viola, R.E. Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family. Chem.Biol.Drug Des., 79:128-136, 2012 Cited by PubMed: 22039970 DOI: 10.1111/j.1747-0285.2011.01267.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation