3PX7

Crystal Structure of covalent complex of topoisomerase 1A with substrate

Summary for 3PX7

• Entry DOI: 10.2210/pdb3px7/pdb
• Related: 1CY0 1CY4 1ECL
• Descriptor: DNA topoisomerase, DNA 5'-D(*TP*TP*GP*GP*G)-3', DNA 5'-D(*A*AP*TP*GP*CP*GP*CP*T)-3', ... (5 entities in total)
• Functional Keywords: topoisomerase, isomerase, isomerase-dna complex, isomerase/dna
• Biological source: Escherichia coli DH1
• Total number of polymer chains: 3
• Total formula weight: 71856.56

Authors

Zhang, Z.,Tse-dinh, Y.C.,Cheng, B. (deposition date: 2010-12-09, release date: 2011-04-20, Last modification date: 2024-10-30)

• Primary citation: Tse-Dinh, Y.C.,Zhang, Z.,Cheng, B.; Structure of E. coli Topoisomerase I Trapped as Covalent Complex Intermediate with Cleaved DNA; To be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)