3PWD

Crystal structure of maize CK2 in complex with NBC (Z1)

3PWD の概要

• エントリーDOI: 10.2210/pdb3pwd/pdb
• 分子名称: Casein kinase II subunit alpha, 8-hydroxy-4-methyl-9-nitro-2H-benzo[g]chromen-2-one (3 entities in total)
• 機能のキーワード: protein kinase, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Zea mays (maize)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39562.39

構造登録者

Battistutta, R.,Mazzorana, M. (登録日: 2010-12-08, 公開日: 2011-11-02, 最終更新日: 2024-03-20)

• 主引用文献: Sarno, S.,Mazzorana, M.,Traynor, R.,Ruzzene, M.,Cozza, G.,Pagano, M.A.,Meggio, F.,Zagotto, G.,Battistutta, R.,Pinna, L.A.; Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A; Cell.Mol.Life Sci., 69:449-460, 2012; PubMed: 21720886; DOI: 10.1007/s00018-011-0758-7

実験手法

X-RAY DIFFRACTION (2.2 Å)