3PUQ
CEKDM7A from C.Elegans, complex with alpha-KG
Summary for 3PUQ
Entry DOI | 10.2210/pdb3puq/pdb |
Related | 3PUR |
Descriptor | Lysine-specific demethylase 7 homolog, FE (II) ION, ZINC ION, ... (6 entities in total) |
Functional Keywords | demethylase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Caenorhabditis elegans (nematode) |
Cellular location | Nucleus: Q9GYI0 |
Total number of polymer chains | 2 |
Total formula weight | 124740.70 |
Authors | |
Primary citation | Xu, W.,Yang, H.,Liu, Y.,Yang, Y.,Wang, P.,Kim, S.-H.,Ito, S.,Yang, C.,Wang, P.,Xiao, M.-T.,Liu, L.-X.,Jiang, W.-Q.,Liu, J.,Zhang, J.-Y.,Wang, B.,Frye, S.,Zhang, Y.,Xu, Y.-H.,Lei, Q.-Y.,Guan, K.-L.,Zhao, S.-M.,Xiong, Y. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases Cancer Cell, 19:17-30, 2011 Cited by PubMed: 21251613DOI: 10.1016/j.ccr.2010.12.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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