3PTZ
Role of Packing Defects in the Evolution of Allostery and Induced Fit in Human UDP-Glucose Dehydrogenase.
Summary for 3PTZ
Entry DOI | 10.2210/pdb3ptz/pdb |
Related | 3PRJ |
Descriptor | UDP-glucose 6-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE, ... (4 entities in total) |
Functional Keywords | feedback inhibition, rossmann fold, nucleotide sugar dehydrogenase, nad binding protein, cytosol, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 337761.83 |
Authors | Kadirvelraj, R.,Wood, Z.A. (deposition date: 2010-12-03, release date: 2011-06-15, Last modification date: 2023-09-06) |
Primary citation | Kadirvelraj, R.,Sennett, N.C.,Polizzi, S.J.,Weitzel, S.,Wood, Z.A. Role of Packing Defects in the Evolution of Allostery and Induced Fit in Human UDP-Glucose Dehydrogenase. Biochemistry, 50:5780-5789, 2011 Cited by PubMed: 21595445DOI: 10.1021/bi2005637 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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