3PSU

HIV-1 protease in complex with an isobutyl decorated oligoamine (symmetric binding mode)

Summary for 3PSU

• Entry DOI: 10.2210/pdb3psu/pdb
• Related: 3BGB
• Descriptor: Protease, N,N'-(iminodiethane-2,1-diyl)bis[4-amino-N-(2-methylpropyl)benzenesulfonamide], CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus type 1 (HIV-1)
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367
• Total number of polymer chains: 1
• Total formula weight: 11364.94

Authors

Lindemann, I.,Heine, A.,Klebe, G. (deposition date: 2010-12-02, release date: 2011-12-07, Last modification date: 2023-11-01)

• Primary citation: Lindemann, I.,Linde, K.,Sammet, B.,Heine, A.,Diederich, W.E.,Klebe, G.; Multiple binding modes of a symmetric inhibitor in HIV-1 protease; To be Published,

Experimental method

X-RAY DIFFRACTION (2.07 Å)