3PSU
HIV-1 protease in complex with an isobutyl decorated oligoamine (symmetric binding mode)
Summary for 3PSU
Entry DOI | 10.2210/pdb3psu/pdb |
Related | 3BGB |
Descriptor | Protease, N,N'-(iminodiethane-2,1-diyl)bis[4-amino-N-(2-methylpropyl)benzenesulfonamide], CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus type 1 (HIV-1) |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367 |
Total number of polymer chains | 1 |
Total formula weight | 11364.94 |
Authors | Lindemann, I.,Heine, A.,Klebe, G. (deposition date: 2010-12-02, release date: 2011-12-07, Last modification date: 2023-11-01) |
Primary citation | Lindemann, I.,Linde, K.,Sammet, B.,Heine, A.,Diederich, W.E.,Klebe, G. Multiple binding modes of a symmetric inhibitor in HIV-1 protease To be Published, |
Experimental method |
Structure validation
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