3PRJ

Role of Packing Defects in the Evolution of Allostery and Induced Fit in Human UDP-Glucose Dehydrogenase.

3PRJ の概要

• エントリーDOI: 10.2210/pdb3prj/pdb
• 関連するPDBエントリー: 3PTZ
• 分子名称: UDP-glucose 6-dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE, ... (4 entities in total)
• 機能のキーワード: feedback inhibition, rossmann fold, nucleotide sugar dehydrogenase, nad binding, cytosol, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 337773.93

構造登録者

Kadirvelraj, R.,Wood, Z.A. (登録日: 2010-11-29, 公開日: 2011-06-15, 最終更新日: 2024-02-21)

• 主引用文献: Kadirvelraj, R.,Sennett, N.C.,Polizzi, S.J.,Weitzel, S.,Wood, Z.A.; Role of Packing Defects in the Evolution of Allostery and Induced Fit in Human UDP-Glucose Dehydrogenase.; Biochemistry, 50:5780-5789, 2011; PubMed: 21595445; DOI: 10.1021/bi2005637

実験手法

X-RAY DIFFRACTION (3.1 Å)