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3POJ

Crystal structure of MASP-1 CUB2 domain bound to Ethylamine

Summary for 3POJ
Entry DOI10.2210/pdb3poj/pdb
Related3POB 3POF
DescriptorMannan-binding lectin serine protease 1, CALCIUM ION, ETHANAMINE, ... (6 entities in total)
Functional Keywordscub domain, ca2+ binding site, complex with ethylamine, complement protein, lectin pathway of complement, mbl, mbp, ficolins, bloodstream, hydrolase
Biological sourceRattus norvegicus (brown rat,rat,rats)
Cellular locationSecreted: Q8CHN8
Total number of polymer chains2
Total formula weight26622.53
Authors
Gingras, A.R.,Moody, P.C.E.,Wallis, R. (deposition date: 2010-11-22, release date: 2011-08-24, Last modification date: 2023-09-06)
Primary citationGingras, A.R.,Girija, U.V.,Keeble, A.H.,Panchal, R.,Mitchell, D.A.,Moody, P.C.,Wallis, R.
Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19:1635-1643, 2011
Cited by
PubMed: 22078562
DOI: 10.1016/j.str.2011.08.014
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.451 Å)
Structure validation

217705

數據於2024-03-27公開中

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