3POE

Crystal structure of the MASP-1 CUB2 domain bound to Ca2+

Summary for 3POE

Entry DOI	10.2210/pdb3poe/pdb
Related	3POB
Descriptor	Mannan-binding lectin serine protease 1, CALCIUM ION (3 entities in total)
Functional Keywords	cub domain, ca2+ binding site, complement protein, lectin pathway of complement, mbl, mbp, bloodstream, hydrolase
Biological source	Rattus norvegicus (brown rat,rat,rats)
Cellular location	Secreted: Q8CHN8
Total number of polymer chains	1
Total formula weight	13171.67
Authors	Gingras, A.R.,Moody, P.C.E.,Wallis, R. (deposition date: 2010-11-22, release date: 2011-08-24, Last modification date: 2023-09-06)
Primary citation	Gingras, A.R.,Girija, U.V.,Keeble, A.H.,Panchal, R.,Mitchell, D.A.,Moody, P.C.,Wallis, R. Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation. Structure, 19:1635-1643, 2011 Cited by PubMed: 22078562 DOI: 10.1016/j.str.2011.08.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.501 Å)

Structure validation