3POC

The crystal structure of the D307A mutant of alpha-Glucosidase (FAMILY 31) from Ruminococcus obeum ATCC 29174 in complex with acarbose

Replaces:  3NQQ

Summary for 3POC

• Entry DOI: 10.2210/pdb3poc/pdb
• Related: 3NQQ
• Related PRD ID: PRD_900007
• Descriptor: alpha-Glucosidase, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, multi-domain, alpha-glucosidase, cytoplasmic, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Ruminococcus obeum
• Total number of polymer chains: 2
• Total formula weight: 156371.41

Authors

Tan, K.,Tesar, C.,Wilton, R.,Keigher, L.,Babnigg, G.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2010-11-22, release date: 2011-01-26, Last modification date: 2023-09-06)

• Primary citation: Tan, K.,Tesar, C.,Wilton, R.,Keigher, L.,Babnigg, G.,Joachimiak, A.; The crystal structure of the D307A mutant of alpha-Glucosidase (FAMILY 31) from Ruminococcus obeum ATCC 29174 in complex with acarbose; To be Published,

Experimental method

X-RAY DIFFRACTION (1.99 Å)