3PNW

Crystal Structure of the tudor domain of human TDRD3 in complex with an anti-TDRD3 FAB

3PNW の概要

• エントリーDOI: 10.2210/pdb3pnw/pdb
• 分子名称: FAB light chain, FAB heavy chain, Tudor domain-containing protein 3, ... (5 entities in total)
• 機能のキーワード: fab, structural genomics consortium, antibody, sgc, protein binding-immune system complex, protein binding/immune system
• 由来する生物種: Homo Sapiens, synthetic construct; 詳細
• 細胞内の位置: Cytoplasm : Q9H7E2
• タンパク質・核酸の鎖数: 24
• 化学式量合計: 480293.69

構造登録者

Loppnau, P.,Tempel, W.,Wernimont, A.K.,Lam, R.,Ravichandran, M.,Adams-Cioaba, M.A.,Persson, H.,Sidhu, S.S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Cossar, D.,Structural Genomics Consortium (SGC) (登録日: 2010-11-19, 公開日: 2010-12-01, 最終更新日: 2023-09-06)

• 主引用文献: Persson, H.,Ye, W.,Wernimont, A.,Adams, J.J.,Koide, A.,Koide, S.,Lam, R.,Sidhu, S.S.; CDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic Antibodies.; J.Mol.Biol., 425:803-811, 2013; PubMed: 23219464; DOI: 10.1016/j.jmb.2012.11.037

実験手法

X-RAY DIFFRACTION (2.05 Å)