3PNA
Crystal Structure of cAMP bound (91-244)RIa Subunit of cAMP-dependent Protein Kinase
Summary for 3PNA
Entry DOI | 10.2210/pdb3pna/pdb |
Related | 1NE4 1RGS |
Descriptor | cAMP-dependent protein kinase type I-alpha regulatory subunit, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | beta-barrel, camp-binding, catalytic subunit, transferase |
Biological source | Bos taurus (bovine,cow,domestic cattle,domestic cow) |
Total number of polymer chains | 2 |
Total formula weight | 35429.63 |
Authors | Kim, C.,Taylor, S. (deposition date: 2010-11-18, release date: 2011-02-09, Last modification date: 2024-02-21) |
Primary citation | Badireddy, S.,Yunfeng, G.,Ritchie, M.,Akamine, P.,Wu, J.,Kim, C.W.,Taylor, S.S.,Qingsong, L.,Swaminathan, K.,Anand, G.S. Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design. Mol Cell Proteomics, 10:M110.004390-M110.004390, 2011 Cited by PubMed: 21081668DOI: 10.1074/mcp.M110.004390 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.503 Å) |
Structure validation
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