3PLN

Crystal structure of Klebsiella pneumoniae UDP-glucose 6-dehydrogenase complexed with UDP-glucose

Summary for 3PLN

• Entry DOI: 10.2210/pdb3pln/pdb
• Related: 3PLR
• Descriptor: UDP-glucose 6-dehydrogenase, URIDINE-5'-MONOPHOSPHATE (3 entities in total)
• Functional Keywords: rossmann fold, dehydrogenase, oxidoreductase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 47709.84

Authors

Chen, Y.-Y.,Ko, T.-P.,Lin, C.-H.,Chen, W.-H.,Wang, A.H.-J. (deposition date: 2010-11-15, release date: 2011-09-28, Last modification date: 2023-11-01)

• Primary citation: Chen, Y.Y.,Ko, T.P.,Lin, C.H.,Chen, W.H.,Wang, A.H.; Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.; J.Struct.Biol., 175:300-310, 2011; PubMed: 21536136; DOI: 10.1016/j.jsb.2011.04.010

Experimental method

X-RAY DIFFRACTION (1.5 Å)