3PKN

Crystal structure of MLLE domain of poly(A) binding protein in complex with PAM2 motif of La-related protein 4 (LARP4)

3PKN の概要

• エントリーDOI: 10.2210/pdb3pkn/pdb
• 分子名称: Polyadenylate-binding protein 1, La-related protein 4, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: all helical domain, protein binding, la-related protein 4
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: P11940
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 11186.60

構造登録者

Xie, J.,Kozlov, G.,Gehring, K. (登録日: 2010-11-11, 公開日: 2011-01-12, 最終更新日: 2023-09-06)

• 主引用文献: Yang, R.,Gaidamakov, S.A.,Xie, J.,Lee, J.,Martino, L.,Kozlov, G.,Crawford, A.K.,Russo, A.N.,Conte, M.R.,Gehring, K.,Maraia, R.J.; La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability.; Mol.Cell.Biol., 31:542-556, 2011; PubMed: 21098120; DOI: 10.1128/MCB.01162-10

実験手法

X-RAY DIFFRACTION (1.8 Å)