3PIQ
Crystal structure of human 2909 Fab, a quaternary structure-specific antibody against HIV-1
Summary for 3PIQ
Entry DOI | 10.2210/pdb3piq/pdb |
Descriptor | Human monoclonal antibody 2909 Fab heavy chain, Human monoclonal antibody 2909 Fab light chain (2 entities in total) |
Functional Keywords | monoclonal antibody, neutralizing, hiv-1, quaternary epitope, trimeric envelope spike, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 12 |
Total formula weight | 284943.33 |
Authors | Changela, A.,Gorny, M.K.,Zolla-Pazner, S.,Kwong, P.D. (deposition date: 2010-11-07, release date: 2011-01-05, Last modification date: 2023-09-06) |
Primary citation | Changela, A.,Wu, X.,Yang, Y.,Zhang, B.,Zhu, J.,Nardone, G.A.,O'Dell, S.,Pancera, M.,Gorny, M.K.,Phogat, S.,Robinson, J.E.,Stamatatos, L.,Zolla-Pazner, S.,Mascola, J.R.,Kwong, P.D. Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1. J.Virol., 85:2524-2535, 2011 Cited by PubMed: 21191009DOI: 10.1128/JVI.02335-10 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.325 Å) |
Structure validation
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