3PGL
Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole
Summary for 3PGL
Entry DOI | 10.2210/pdb3pgl/pdb |
Related | 1T9Z 2GHQ 2GHT 3L0B 3L0C 3L0Y |
Descriptor | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, 2-[(R)-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl]-1H-benzimidazole, ... (4 entities in total) |
Functional Keywords | had family, insertion domain, ctd phosphatase, neuronal silencer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q9GZU7 |
Total number of polymer chains | 2 |
Total formula weight | 41887.24 |
Authors | Zhang, M.,Cho, E.J.,Burstein, G.,Siegel, D.,Zhang, Y. (deposition date: 2010-11-02, release date: 2011-03-09, Last modification date: 2024-02-21) |
Primary citation | Zhang, M.,Cho, E.J.,Burstein, G.,Siegel, D.,Zhang, Y. Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor. Acs Chem.Biol., 6:511-519, 2011 Cited by PubMed: 21348431DOI: 10.1021/cb100357t PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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