3PEH
Crystal Structure of the N-terminal domain of an HSP90 from Plasmodium Falciparum, PFL1070c in the presence of a thienopyrimidine derivative
Summary for 3PEH
Entry DOI | 10.2210/pdb3peh/pdb |
Related | 3PEJ |
Descriptor | Endoplasmin homolog, 2-amino-4-{2,4-dichloro-5-[2-(diethylamino)ethoxy]phenyl}-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide, SULFATE ION (3 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, heat shock protein, chaperone, atp binding |
Biological source | Plasmodium falciparum 3D7 |
Total number of polymer chains | 2 |
Total formula weight | 65287.58 |
Authors | Wernimont, A.K.,Tempel, W.,Hutchinson, A.,Weadge, J.,Cossar, D.,MacKenzie, F.,Vedadi, M.,Senisterra, G.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Wyatt, P.G.,Fairlamb, A.H.,MacKenzie, C.,Ferguson, M.A.J.,Hui, R.,Pizarro, J.C.,Hills, T.,Structural Genomics Consortium (SGC) (deposition date: 2010-10-26, release date: 2010-11-17, Last modification date: 2023-09-06) |
Primary citation | Wernimont, A.K.,Tempel, W.,Hutchinson, A.,Weadge, J.,Cossar, D.,MacKenzie, F.,Vedadi, M.,Senisterra, G.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Wyatt, P.G.,Fairlamb, A.H.,MacKenzie, C.,Ferguson, M.A.J.,Hui, R.,Pizarro, J.C.,Hills, T. Crystal Structure of the N-terminal domain of an HSP90 from Plasmodium Falciparum, PFL1070c in the presence of a thienopyrimidine derivative To be Published, |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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