3PEH

Crystal Structure of the N-terminal domain of an HSP90 from Plasmodium Falciparum, PFL1070c in the presence of a thienopyrimidine derivative

3PEH の概要

• エントリーDOI: 10.2210/pdb3peh/pdb
• 関連するPDBエントリー: 3PEJ
• 分子名称: Endoplasmin homolog, 2-amino-4-{2,4-dichloro-5-[2-(diethylamino)ethoxy]phenyl}-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide, SULFATE ION (3 entities in total)
• 機能のキーワード: structural genomics, structural genomics consortium, sgc, heat shock protein, chaperone, atp binding
• 由来する生物種: Plasmodium falciparum 3D7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65287.58

構造登録者

Wernimont, A.K.,Tempel, W.,Hutchinson, A.,Weadge, J.,Cossar, D.,MacKenzie, F.,Vedadi, M.,Senisterra, G.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Wyatt, P.G.,Fairlamb, A.H.,MacKenzie, C.,Ferguson, M.A.J.,Hui, R.,Pizarro, J.C.,Hills, T.,Structural Genomics Consortium (SGC) (登録日: 2010-10-26, 公開日: 2010-11-17, 最終更新日: 2023-09-06)

• 主引用文献: Wernimont, A.K.,Tempel, W.,Hutchinson, A.,Weadge, J.,Cossar, D.,MacKenzie, F.,Vedadi, M.,Senisterra, G.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Wyatt, P.G.,Fairlamb, A.H.,MacKenzie, C.,Ferguson, M.A.J.,Hui, R.,Pizarro, J.C.,Hills, T.; Crystal Structure of the N-terminal domain of an HSP90 from Plasmodium Falciparum, PFL1070c in the presence of a thienopyrimidine derivative; To be Published,

実験手法

X-RAY DIFFRACTION (2.75 Å)