3PDN
Crystal structure of SmyD3 in complex with methyltransferase inhibitor sinefungin
Summary for 3PDN
Entry DOI | 10.2210/pdb3pdn/pdb |
Descriptor | SET and MYND domain-containing protein 3, SINEFUNGIN, GLYCEROL, ... (6 entities in total) |
Functional Keywords | rossmann fold, zinc finger, methyltransferase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9H7B4 |
Total number of polymer chains | 1 |
Total formula weight | 50356.91 |
Authors | Sirinupong, N.,Brunzelle, J.,Yang, Z. (deposition date: 2010-10-23, release date: 2010-11-17, Last modification date: 2024-02-21) |
Primary citation | Sirinupong, N.,Brunzelle, J.,Doko, E.,Yang, Z. Structural Insights into the Autoinhibition and Posttranslational Activation of Histone Methyltransferase SmyD3. J.Mol.Biol., 406:149-159, 2011 Cited by PubMed: 21167177DOI: 10.1016/j.jmb.2010.12.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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