3PCV

Crystal structure analysis of human leukotriene C4 synthase at 1.9 angstrom resolution

Summary for 3PCV

• Entry DOI: 10.2210/pdb3pcv/pdb
• Related: 2PNO
• Descriptor: Leukotriene C4 synthase, GLUTATHIONE, DODECYL-BETA-D-MALTOSIDE, ... (7 entities in total)
• Functional Keywords: membrane protein, helix bundle, homo trimer, mgst, mapeg, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus outer membrane; Multi-pass membrane protein: Q16873
• Total number of polymer chains: 1
• Total formula weight: 23776.03

Authors

Saino, H.,Ago, H.,Miyano, M. (deposition date: 2010-10-22, release date: 2011-03-16, Last modification date: 2023-11-01)

• Primary citation: Saino, H.,Ukita, Y.,Ago, H.,Irikura, D.,Nisawa, A.,Ueno, G.,Yamamoto, M.,Kanaoka, Y.,Lam, B.K.,Austen, K.F.,Miyano, M.; The catalytic architecture of leukotriene C4 synthase with two arginine residues; J.Biol.Chem., 286:16392-16401, 2011; PubMed: 21454538; DOI: 10.1074/jbc.M110.150177

Experimental method

X-RAY DIFFRACTION (1.9 Å)